After completing a quick online medical quiz, a licensed provider
reviews your eligibility.
TMates offers bothlow
‑
dose oral or injectable semaglutide,
customized to your needs. They deliver the medication to your door
—no clinic visits required.
The program includes telemedicine consultations, nutrition and
exercise coaching, and continuous medical oversight throughout
your journey.
A standout feature: 24/7 access to U.S.
‑
based medical support,
making it convenient and discreet.
Mechanism: How Semaglutide Supports Weight Loss
Semaglutide mimics the natural hormone GLP
‑
1 by:
Increasing Insulin Secretion & Suppressing Glucagon, helping
stabilize blood sugar levels.
Reducing Appetite and Delaying Gastric Emptying, meaning you eat
less and feel full longer.
Shifting Eating Behavior, decreasing cravings, increasing satiety,
and improving eating control.
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Clinical Effectiveness & Trial Insights
Several Phase 3STEPtrials demonstrate semaglutide’s weight-loss
impact:
STEP 1 68 weeks): 14.9% average weight reduction vs. 2.4%
with placebo.
STEP 3 16.0% loss vs. 5.7% with placebo.
STEP 4 (withdrawal trial): Continuing treatment led to sustained
7.9% loss; switching to placebo resulted in 6.9 kg weight gain.
STEP 5 104 weeks): 15.2% weight reduction maintained long-
term.
Other studies show:
In clinical settings,6
‐
monthweight loss averages ranged
around10.9%, with significant portions achieving ≥5%, ≥10%, and
≥15% weight loss.
Across68 weeks, semaglutide-treated individuals showed more
weight loss versus lifestyle changes alone, where only 2.4% was
lost.
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TMates Program: Structure and Process
Onboarding: A brief medical intake, consultation, and eligibility
evaluation.